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Effect of membrane morphology and operation on protein deposition in ultrafiltration membranes
Author(s) -
Chen V.,
Kim K. J.,
Fane A. G.
Publication year - 1995
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260470208
Subject(s) - ultrafiltration (renal) , membrane , morphology (biology) , deposition (geology) , chemistry , chemical engineering , biophysics , materials science , chromatography , biology , biochemistry , engineering , paleontology , genetics , sediment
Membrane morphology is compared to protein depostion under passive adsorption and ultrafiltration conditions. Solute resistance of protein deposits for membranes of varying roughness, structure, and permeability can vary dramatically with operating conditions. Using Brunauer–Emmett–Teller adsorption isotherm (BET), study of the internal area and accessibility of several uttrafiltration membranes to protein deposition allows better understanding of the fouling mechanisms and interpretation of adsorbed protein quantities. © 1995 John Wiley & Sons, Inc.