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The Monod equation and mass transfer
Author(s) -
Merchuk J. C.,
Asenjo J. A.
Publication year - 1995
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260450113
Subject(s) - mass transfer , substrate (aquarium) , thermodynamics , constant (computer programming) , interpretation (philosophy) , growth rate , reaction rate constant , kinetic energy , chemistry , phenomenological model , kinetics , physics , mathematics , philosophy , classical mechanics , statistics , ecology , computer science , biology , geometry , linguistics , programming language
An alternative interpretation of the growth rate–substrate concentration dependence is presented. This is based on the assumption that the main factors affecting growth rate are transfer of substrate from the medium and the maximum growth velocity, which is that observed when no substrate limitations occur. This approach allows the approximate prediction of one of the two kinetic constants required, and may be of great use, especially for continuous cultures. It is the first attempt to provide a phenomenological explanation for the large variations observed in the values of the Monod constant, K s , reported in the literature. © 1995 John Wiley & Sons, Inc.