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Studies of on‐line viable yeast biomass with a capacitance biomass monitor
Author(s) -
Austin Glen D.,
Watson Rodney W. J.,
D'Amore Tony
Publication year - 1994
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260430411
Subject(s) - biomass (ecology) , line (geometry) , biomass fuels , yeast , environmental science , capacitance , pulp and paper industry , microbiology and biotechnology , biology , chemistry , ecology , engineering , biochemistry , mathematics , electrode , geometry
A commercially available biomass monitor has been employed in a number of applications. For capacitance monitors, a relationship between capacitance measurement and cell counts or colony forming units has been reported in the literature. However, for use as an online instrument, a more practical correlation with the biomass concentration is needed. In this study, we followed the batch growth of brewer's yeast and a correlation with viable biomass concentration (g DW/L) was demonstrated. This correlation was utilized with the capacitance biomass monitor in a control loop to maintain setpoint biomass levels in a cyclic reactor under perturbations. Not only did the system demonstrate the capability of the biomass monitor to control biomass in such a system, but it also confirmed the correlation reported in our earlier work. © 1994 John Wiley & Sons, Inc.