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Continuous measurement of microbial heat production in laboratory fermentors
Author(s) -
van Kleeff B. H. A.,
Kuenen J. G.,
Heijnen J. J.
Publication year - 1993
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260410506
Subject(s) - biochemical engineering , production (economics) , microbiology and biotechnology , biology , environmental science , engineering , economics , macroeconomics
The possibility of continuously measuring the heat produced by microorganisms in an ordinary laboratory fermentor was studies. An inventory of the heat flows influencing the temperature of the culture was made. The magnitude and standard deviation in these heat flows were studied from theoretical and practical viewpoints. Calibration procedures were tested, and a model describing the heat flows in steady state and during dynamic conditions was made. Microbial heat production could be calculated accurately with the help of this model, appropriate temperature measurements, and equipment properties measured during the calibration procedures. It was found that the measurement of heat production could be done with an accuracy similar to that in the O 2 uptake measurement. © 1993 John Wiley & Sons, Inc.