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Immobilized catalase: Deactivation and reactor stability
Author(s) -
Vasudeven P. T.,
Weiland R. H.
Publication year - 1993
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260410209
Subject(s) - catalase , chemistry , stability (learning theory) , biochemical engineering , chromatography , enzyme , biochemistry , computer science , engineering , machine learning
The quasi‐steady behavior of a continuous flow reactor in which hydrogen peroxide is decomposed by immobilized catalase is investigated. Under certain conditions, reactors involving such substrate‐inhibited, self‐poisoning reactions are susceptible to suddne failure and the reactor moves catastrophically from high‐ to low‐conversion quasi‐steady states. This exchange‐of‐steady‐states phenomenon is ex‐amined in the light of experimental evidence for the enzyme catalase from bovine liver. © 1993 John Wiley & Sons, Inc.