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Control of Escherichia coli–Candida utilis continuous, competitive mixed‐culture system using the dynamic matrix control algorithm
Author(s) -
Goochee Charles F.,
Hatch Randolph T.,
Cadman Theodore W.
Publication year - 1989
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260330306
Subject(s) - matrix (chemical analysis) , escherichia coli , yeast , metastability , microbiology and biotechnology , biology , chemistry , algorithm , computer science , chromatography , biochemistry , organic chemistry , gene
Abstract The control of the continuous, competitive mixed culture of the yeast Candida utilis (ATCC 8205) and the bacterium Escherichia coli B/r (ATCC 12407) was examined. A modified version of the dynamic matrix control (DMC) algorithm was tested in simulation and then was successfully implemented. This represents the first report of the location and stabilization of a competitive mixed culture at a metastable equilibrium point using automatic control.