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Design and mathematical description of differential contactors used in extractive fermentations
Author(s) -
Roffler Stephen R.,
Wilke Charles R.,
Blanch Harvey W.
Publication year - 1988
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260320209
Subject(s) - contactor , raffinate , stripping (fiber) , chemistry , substrate (aquarium) , limiting , chromatography , constant (computer programming) , product (mathematics) , thermodynamics , process engineering , extraction (chemistry) , materials science , mathematics , computer science , mechanical engineering , physics , power (physics) , oceanography , geometry , composite material , engineering , programming language , geology
The performance of differential contactors for use in extractive fermentation is complicated by the effects of product formation in the contactor. When product formation is significant, approximate analytical solutions are presented for the performance of the contactor for two limiting cases: high and low substrate concentrations. When products are formed at a constant rate, there is a minimum raffinate solute concentration that can be obtained, in contrast to the behavior of a column in the absence of product formation. General equations describing the behavior of the system for product formation with backmixing in both phases are presented. The case of a stripping factor not equal to unity is considered.