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The electrochemical regeneration of NAD + revisited
Author(s) -
Laval JeanMarc,
Bourdillon Christian,
Moiroux Jacques
Publication year - 1987
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260300203
Subject(s) - nad+ kinase , regeneration (biology) , electrochemistry , cofactor , chemistry , yield (engineering) , enzyme , biochemistry , electrode , materials science , biology , microbiology and biotechnology , metallurgy
Abstract An actual yield of 99.97% (i.e., 3000 potential regenerating cycles) has been obtained for the electrochemical regeneration of NAD + . The deactivation of the coenzyme is not related to the number of cycles; it is only time dependent. For biotechnological applications, these results show that electrochemical regeneration can compete with enzymatic regeneration for selective oxidation by dehydrogenases.