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Effect of cycling on final mixed culture fate
Author(s) -
Stephens M. L.,
Lyberatos G.
Publication year - 1987
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260290603
Subject(s) - cycling , dilution , adaptability , substrate (aquarium) , extinction (optical mineralogy) , lag , biological system , environmental science , diagram , temperature cycling , chemistry , ecology , thermodynamics , biology , mathematics , computer science , mineralogy , statistics , physics , computer network , archaeology , history , thermal
Cycling in feed substrate concentration and dilution rate is examined as a means of modifying the final fate of a mixed culture. It is shown for the case where the specific growth rate of one species is always greater than that of the second that no cycling strategy will provide the desired extinction of the faster growing species unless time delay is included in the modeling. To account for the time lag in adjusting organism metabolic activities to environmental changes, an adaptability parameter is introduced. Numerical simulations are carried out and an operating diagram indicating the conditions under which the desired extinction occurs is constructed. Cycling in feed substrate concentration and dilution rate are both found to produce the desired result.