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Determination of reactor biomass by acoustic resonance densitometry
Author(s) -
BlakeColeman B. C.,
Clarke D. J.,
Calder M. R.,
Moody S. C.
Publication year - 1986
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260280816
Subject(s) - densitometry , bioreactor , biomass (ecology) , dilution , fermentation , range (aeronautics) , process engineering , environmental science , chromatography , chemistry , computer science , materials science , biological system , optics , physics , biology , engineering , composite material , biochemistry , agronomy , organic chemistry , thermodynamics
Acoustic resonance densitometry (ARD) is reported as a method suitable not only for precise investigations into changes of specific gravity in bioreactor media but also as a technique able to provide an accurate wide range and direct determination of cellular mass in fermentation processes. It is further shown that this method can replace present optical procedures, minimizing dilution errors and operator involvement and is suitable for development as an on‐line biomass monitoring system.