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A simplified calculation method applied to enzyme inactivation during drying
Author(s) -
Liou J. K.,
Luyben K. Ch. A. M.,
Bruin S.
Publication year - 1985
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260270113
Subject(s) - diffusion , nonlinear system , chemistry , function (biology) , enzyme , lipoxygenase , calcium alginate , power function , thermodynamics , calcium , chromatography , biological system , mathematics , biochemistry , mathematical analysis , physics , biology , organic chemistry , quantum mechanics , evolutionary biology
An approximate method for solving the nonlinear diffusion problem in the case of a power‐function variation of the diffusion coefficient with concentration has been applied to a drying process with simultaneous enzyme inactivation. Experimental results obtained by air drying of soybean lipoxygenase entrapped in a glucose calcium‐alginate gel are in good agreement with the predicted behavior, whereas hardly any differences occur between the results obtained with the approximate method and those obtained by a numerical solution of the original model.