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Practical reactor systems for yeast cell immobilization using biomass support particles
Author(s) -
Black G. M.,
Webb C.,
Matthews T. M.,
Atkinson B.
Publication year - 1984
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260260205
Subject(s) - industrial fermentation , biomass (ecology) , bioreactor , fluidized bed , yeast , fermentation , buoyancy , particle (ecology) , process engineering , waste management , chemistry , environmental science , chemical engineering , engineering , biology , mechanics , biochemistry , ecology , physics , organic chemistry , agronomy
Abstract The technique of cell immobilization using porous support particles (biomass support particles) has been successfully applied to yeast cells. Two reactor configurations exploiting the use of these particles have been developed and assessed for use in aseptic yeast fermentations. A liquid‐fluidized bed fermenter has been devised for use with particles denser than the fermentation liquor whilst a gas‐stirred circulating bed fermenter proved suitable for particles of essentially neutral buoyancy. Both systems have been operated successfully for extended periods of continuous operation. The utilization of biomass support particle technology in such reactors provides a practical and robust system for immobilized cell reactors. This technology offers significant opportunities for further development.