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A new function for overall optimization of yeast production
Author(s) -
Klibansky Miriam M.,
Otero Miguel A.,
González Leonel F.
Publication year - 1983
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260251102
Subject(s) - production (economics) , yeast , biochemical engineering , function (biology) , chemistry , microbiology and biotechnology , biological system , computational biology , biology , biochemistry , engineering , economics , macroeconomics
The influence of several operating variables on the productivity and nutritional quality of Candida utilis under carbon‐limited growth conditions was studied. Four responses were analyzed: biomass yield ( Y ), in vitro dry matter digestibility ( d ), nucleic acid cotents, and protein content ( P ). Three operating variables were studied: dilution rate, temperature, and carbon‐nitrogen ratio in the growth medium. Correlation describing the influence of operating variables on the studied response parameters were developed. From these correlations response surfaces were drawn. A new function, α = PdY , is proposed as a more comprehensive criterion for selecting the optimal conditions under the constraint of satisfying multiple objectives. It is demonstrated to be superior to the yield coefficient alone in this respect, since it accounts for factors that are important to the nutritional aspects of the process.