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Application of a noninhibitory growth model to predict the transient response in a chemostat
Author(s) -
Chiam H. F.,
Harris I. J.
Publication year - 1983
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260250614
Subject(s) - chemostat , transient (computer programming) , steady state (chemistry) , biological system , kinetic energy , transient response , biochemical engineering , control theory (sociology) , computer science , environmental science , chemistry , biology , engineering , physics , control (management) , genetics , quantum mechanics , artificial intelligence , bacteria , electrical engineering , operating system
A method of adapting a kinetic model based on steady‐state chemostat data to predict the transient performance of a chemostat culture is presented. The proposal provides for a time delay which can be considered equivalent to a period of reduced activity of the organism subsequent to the introduction of a step change in operating conditions. The adapted kinetic model gives substantially better performance in predicting the transient response of an experimental system than the unmodified kinetic model.

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