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Ethanol fermentation with cell recycling: Computer simulation
Author(s) -
Lee J. M.,
Pollard J. F.,
Coulman G. A.
Publication year - 1983
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260250215
Subject(s) - industrial fermentation , yeast , fermentation , productivity , ethanol , chemistry , ethanol fermentation , bioreactor , biochemistry , pulp and paper industry , engineering , organic chemistry , economics , macroeconomics
A mathematical model for glucose‐to‐ethanol fermentation at high yeast cell concentrations was developed. The feasibility of improving fermenter productivity over that of a conventional continuous‐stirred‐tank fermenter by using multiple stage reactors and yeast cell recycling was predicted by computer simulation. The optimum size distribution for multistage fermentors was obtained for different glucose feedstream concentrations and different glucose conversion levels. Productivity increases over a single‐stage reactor ranged from 1.2–2.0 times. The use of yeast cell recycling to increase cell concentration and productivity increases of over 4.0 times that of a system without recycling.