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Characterization of the two‐phase systems in airlift tower–loop bioreactors during the cultivation of E. coli
Author(s) -
Lippert J.,
Adler I.,
Meyer H. D.,
Lübbert A.,
Schügerl K.
Publication year - 1983
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260250211
Subject(s) - aeration , bioreactor , airlift , dissipation , turbulence , bubble , tower , mechanics , biomass (ecology) , scale up , environmental science , physics , chemistry , thermodynamics , biology , engineering , classical mechanics , ecology , civil engineering , organic chemistry
During the cultivation of E. coli in an airlift tower–loop bioreactor, the following properties were measured: transverse profiles of Sauter bubble diameter, d S ; local relative gas holdup, E G ; bubble rise velocity, u BS ; local mean velocity, ū turbulence intensity, u ′; macrotime scale, T EL ; dissipation time scale, τ E ; power spectrum, E ( n ); and energy dissipation spectrum D ( n ) at different distances from the aerator. The influence, distance from the aerator, absence and/or presnece of cells, and batch and/or continuous‐culture operation on the behavior of the two‐phase system are discussed on the basis of these properties.