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Efficiency of the cyclic batch antibiotic fermentation
Author(s) -
Guthke R.,
Knorre W. A.
Publication year - 1982
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260241002
Subject(s) - fermentation , antibiotics , chemistry , microbiology and biotechnology , food science , biology
For a simple mathematical model of microbial product formation, the productivities of stationary and nonstationary cultivation methods (chemostat and cyclic batch) are compared. Conditions of superiority of the cyclic batch cultivation are characterized. The model includes substrate inhibition of the product formation and the age‐dependent loss of productivity of the culture.