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A study of acetic acid production by immobilized Acetobacter cells: Product inhibition effects
Author(s) -
Ghommidh C.,
Navarro J. M.,
Messing R. A.
Publication year - 1982
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260240907
Subject(s) - acetic acid , chemistry , dilution , adsorption , volumetric flow rate , steady state (chemistry) , chromatography , oxygen , bioreactor , product inhibition , chemical engineering , biochemistry , biophysics , organic chemistry , thermodynamics , biology , physics , engineering , non competitive inhibition , enzyme
Abstract Acetobacter living cells were immobilized by adsorption onto a ceramic support. The effects of acetic acid inhibition have been studied in a fixed‐bed pulsed‐flow reactor. Provided that sufficient oxygen was available, the concentration of acetic acid was found to be independent of the flow rate. Damped oscillations of acetic acid concentration were observed after step changes in dilution rate. The theoretical model developed from steady‐state data was successful in predicting the experimental dynamic behavior of the reactor.