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Oxygen mass transfer into aerated CMC solutions in a bubble column
Author(s) -
Deckwer W.D.,
NguyenTien K.,
Schumpe A.,
Serpemen Y.
Publication year - 1982
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260240215
Subject(s) - bubble , mass transfer , sparging , penicillium chrysogenum , chemistry , dispersion (optics) , thermodynamics , aeration , oxygen , chromatography , slug flow , analytical chemistry (journal) , viscosity , phase (matter) , flow (mathematics) , mechanics , two phase flow , physics , biochemistry , organic chemistry , optics
Differing findings on the volumetric mass transfer coefficients k L a in CMC solutions in bubble column bioreactors have been reported in the literature. Therefore, oxygen mass transfer was studied again in CMC solutions in a 14‐cm‐i.d. × 270‐cm‐height bubble column using different spargers. The k L a values were determined along with the dispersion coefficients by fitting the prediction of the axial dispersed plug model with the experimental oxygen concentration profiles in the liquid phase. Surprisingly, the obtained liquid phase dispersion coefficients for CMC solution are higher than one would expect from correlations. The k L a data depend largely on the flow regime. In general, they are lower than those reported in the literature. The data for developing slug and established slug flow are dependent on the gas velocity and the effective viscosity of the solution and can br correlated by a simple correlation. This correlation describes k L a values measured on fermentation broth of Penicillium chrysogenum with striking agreement.