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Total containment of a continuous‐flow zonal centrifuge
Author(s) -
Gooders A. P.,
Webb N. L.,
Allen G. J.,
Richards B. M.
Publication year - 1981
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260230102
Subject(s) - centrifuge , filtration (mathematics) , turbine , containment (computer programming) , human decontamination , environmental science , continuous flow , process engineering , waste management , computer science , engineering , mechanical engineering , physics , statistics , mathematics , nuclear physics , biochemical engineering , programming language
A continuous‐flow, high throughput, turbine‐driven zonal centrifuge has been contained for use with biologically hazardous materials. The centrifuge and all ancillary equipment are enclosed in three sealed cabinets that are maintained at negative pressure, decontaminated with ethylene oxide, and provide cooling for the process fluids. Sample handling is semiautomated and remotely controlled for ease of operation and includes an automated decontamination system. The centrifuge subsystems can be decontaminated prior to an engineer servicing the machine, and apparatus is provided for absolute filtration of the centrifuge turbine exhaust.