Premium
On‐line identification of parameters in a fermentation process
Author(s) -
Bravard J. P.,
Cordonnier M.,
Kernevez J. P.,
Lebeault J. M.
Publication year - 1979
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260210712
Subject(s) - fermentation , biomass (ecology) , yield (engineering) , process (computing) , identification (biology) , dry weight , production (economics) , biological system , constant (computer programming) , process engineering , chemistry , biochemical engineering , pulp and paper industry , food science , biology , computer science , agronomy , botany , thermodynamics , engineering , macroeconomics , economics , operating system , programming language , physics
In a fermentation process, the establishment of gas mass balances provides valuable information and allows both measurements concerning the characteristics of the biomass itself and the monitoring of a cultivation process. If the quantity and oxidation level of substances excreted into the fermentation broth are known or constant, the yield factor and the dry cell‐weight production are stoichiometrically related to the quantity of CO 2 evolved and to the quantity of O 2 consumed. Where frequent measurements of both yield factor and dry cell‐weight production are desirable or where rapid adjustment of the parameters is necessary, on‐line identification of these parameters is required, An algorithm allowing the identification of the specific growth rate is presented. Moreover, this technique allows one to estimate the percent protein in the biomass during continuous culture.