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The viscostat: Productstat method of feed‐rate control in continuous fermentations
Author(s) -
Silman R. W.,
Bagley E. B.
Publication year - 1979
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260210204
Subject(s) - chemostat , xanthomonas campestris , fermentation , xanthan gum , viscosity , continuous production , bioreactor , microbiology and biotechnology , food science , pulp and paper industry , environmental science , biology , botany , bacteria , environmental engineering , rheology , materials science , engineering , genetics , composite material
Xanthan biopolymer has been produced in a single‐stage continuous fermentation with Xanthomonas campestirs NRRL B‐1459, using a viscostal control method instead of the conventional chemostat method. A Bendix Ultraviscoson The mention of firm names or trade products does not imply that they are endorsed or recommended by the U.S. Department of Agriculture over other firms or similar products not mentioned. sensed the fermentor viscosity, and the recorder–controller actuated the feed medium pump in an on–off control mode. Since all continuous fermentations eventually become contaminated or suffer culture variation, this work served also to demonstrate the effectiveness of the viscostat control. Neither the presence of a mold contaminant with specific growth rates lower than that of X. campestris , nor the presence of a bacterial contaminant of specific growth rate greater than X. campestris , affected the maintenance of constant viscosity in this control system.