Premium
The production of foot‐and‐mouth disease virus from BHK 21 C 13 cells grown on the surface of glass spheres
Author(s) -
Spier R. E.,
Whiteside J. P.
Publication year - 1976
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260180505
Subject(s) - monolayer , foot and mouth disease virus , virus , baby hamster kidney cell , yield (engineering) , virology , materials science , biology , chemistry , nanotechnology , composite material
In view of the advantages which are associated with the use of the BHK monolayer cell for the production of foot‐and‐mouth disease (FMD) virus, a unit system using glass spheres was developed to grow BHK monolayer cells and to test the susceptibility of such cells to FMD virus. The yield of cells and their susceptibility compares favorably with BHK monolayer cells which have been grown in Roux bottles.