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Kinetic analysis of Penicillin production by semicontinuous fermenters
Author(s) -
Giona A. R.,
Marrelli L.,
Toro L.,
De Santis R.
Publication year - 1976
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260180404
Subject(s) - biomass (ecology) , penicillin , biochemical engineering , production (economics) , pulp and paper industry , chemistry , process engineering , environmental science , biological system , biology , ecology , biochemistry , engineering , economics , antibiotics , macroeconomics
The relationships between the specific rate of nutrient consumption and biomass growth and between the specific rate of penicillin production and oxygen concentration in the broth are analyzed. The functional dependencies which have been obtained from the experimental data of industrial fermenters are used with the mass balances to develop a model of the behavior of semicontinuous operations. The proposed model allows one to study the influence of some operational parameters. The obtained results agree with the data of industrial processes.