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Cell inactivation by ultrasound
Author(s) -
Dakubu S.
Publication year - 1976
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260180403
Subject(s) - ultrasound , chemistry , microbiology and biotechnology , biophysics , computational biology , biology , medicine , radiology
Cell survival curves have been obtained for Escherichia coli B ( E. coli B) after the sonication of suspensions of the bacteria with continuous wave ultrasound at a fixed frequency of 2 MHz between peak intensities of 8.7 and 2.25 W cm −2 . It was found that under suitable conditions the survival curves were reproducible and it also was found that there was a clear relationship between the rate of inactivation and the peak acoustic intensity of the ultrasound. There appeared to be a lower threshold of peak intensity below which no inactivation was observed.