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Inhibition‐threshold substrate concentrations
Author(s) -
Wayman M.,
Tseng M. C.
Publication year - 1976
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260180308
Subject(s) - substrate (aquarium) , arthrobacter , yeast , methanol , bacterial growth , butanol , pseudomonas , chemistry , bacteria , substrate specificity , chromatography , biology , biochemistry , enzyme , organic chemistry , ethanol , ecology , genetics
A proposed substrate inhibition model (M. C. Tseng and M. Wayman, Can. J. Microbiol. , 21 , 994 (1975)), (1)\documentclass{article}\pagestyle{empty}\begin{document}$$\mu = \mu _{\max} S/\left[{K + S} \right],{\rm when}S < S_\theta $$\end{document}(2)\documentclass{article}\pagestyle{empty}\begin{document}$$\mu = \mu _{\max} S/\left[{K + S} \right] - i\left[{S - S_\theta} \right],{\rm when}S > S_\theta $$\end{document} derived from yeast growth rates has been applied to data for bacterial growth: Pseudomonas methanica grown on methanol and Arthrobacter AK19 grown on n ‐butanol. The model represents the experimental data very well.
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