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A heat transfer study on packed bed reactors of immobilized glucoamylase
Author(s) -
Marsh David R.,
Tsao George T.
Publication year - 1976
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260180306
Subject(s) - packed bed , immobilized enzyme , chromatography , chemistry , porosity , heat transfer , porous glass , work (physics) , chemical engineering , enzyme , materials science , thermodynamics , organic chemistry , physics , engineering
Enzymes are generally sensitive to temperature changes. Porous glass particles used for glucoamylase immobilization are poor thermal conductors and a non‐uniform temperature distribution can conceivably develop in a packed bed reactor of immobilized glucoamylase on porous beads. This study was made to determine experimentally the temperature and concentration profiles in an immobilized glucoamylase column. This work provides a procedure for examining possible heat effects on reactor column performance in enzyme applications.