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The tubular loop batch fermentor: Basic concepts
Author(s) -
Russell T. W. F.,
Dunn I. J.,
Blanch H. W.
Publication year - 1974
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260160909
Subject(s) - impeller , fermentation , scale up , flow (mathematics) , continuous stirred tank reactor , process engineering , bioreactor , loop (graph theory) , scale (ratio) , mechanics , chemistry , engineering , chemical engineering , mechanical engineering , mathematics , physics , food science , organic chemistry , classical mechanics , combinatorics , quantum mechanics
A tubular loop batch fermentor has been designed and constructed, and was found to behave in a similar manner to a conventional stirred tank reactor. It appeared that foaming could be greatly reduced as no air ever encountered the impeller. The fluid mechanics of pipe flow are considerably simpler than tank flow patterns. On this basis a design procedure for a large scale tubular fermentor was outlined, which had considerable advantages over the more complex scale‐up problems of a tank fermentor.