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Influence of intraparticle diffuisional limitation on the observed kinetics of immobilized enzymes and on catalyst design
Author(s) -
Regan D. L.,
Lilly M. D.,
Dunnill P.
Publication year - 1974
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260160808
Subject(s) - enzyme , catalysis , mass transfer , chemistry , kinetics , immobilized enzyme , particle (ecology) , chemical engineering , cellulose , chromatography , porosity , particle size , enzyme kinetics , kinetic energy , organic chemistry , active site , physics , biology , ecology , quantum mechanics , engineering
Numerical solutions to the equations describing simultaneous mass transfer and enzymic reaction within porous spherical particles have been used to examine the effect of enzyme content and other parameters on the kinetic behavior of immobilized enzymes. These solutions have also been compared with experimental data for enzymes immobilized to DEAE‐cellulose particles. The influence of particle size and enzyme content on catalyst design is discussed.