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Reduction of contamination in an industrial fermentation plant
Author(s) -
Bartholomew W. H.,
Engstrom D. E.,
Goodman N. S.,
O'Toole A. L.,
Shelton J. L.,
Tannen L. P.
Publication year - 1974
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260160802
Subject(s) - contamination , gas compressor , environmental science , fermentation , air filter , waste management , pulp and paper industry , chemistry , food science , biology , engineering , mechanical engineering , ecology , inlet
Information is presented concerning revisions of the fermentation air system equipment which improved the sterility situation in the production of monosodium glutamate. Basically, the revision were a relocation and elevation of the intake to the air compressors and installation of a retention chamber after the compressors to take advantage of the heat of compression. The extended high temperature retention ensures sterile air to the final air filter before the fermentor. Contamination losses—mainly from phage—have been materially reduced relative to the level prevailing before the change.