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Mechanical disintegration of microorganisms in an industrial homogenizer
Author(s) -
Mogren Hårkan,
Lindblom Marianne,
Hedenskog Gudmund
Publication year - 1974
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260160208
Subject(s) - homogenizer , agitator , yeast , microorganism , suspension (topology) , volumetric flow rate , chemistry , bioreactor , materials science , chromatography , biology , biochemistry , bacteria , mass transfer , mechanics , physics , mathematics , homotopy , pure mathematics , genetics , organic chemistry
Abstract Disintegration of microorganisms in a continuously working industrial homogenizer has been studied. The homogenizer consists of rotating discs in a cylinder filled with glass beads. Different parameters for disintegration of baker's yeast were investigated. The disintegration process is a first‐order reaction and it is influenced by the flow rate of the suspension and by the agitator speed. At a flow rate of 200 liters/hr about 85% of the yeast cells can be disrupted in a single pass through the disintegrator. This type of disintegrator can be used for disruption of cells in order to produce single‐cell protein, active enzymes and other valuable cell components.