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Model for the growth of aerobic microorganisms under oxygen limiting conditions
Author(s) -
Ryder D. N.,
Sinclair C. G.
Publication year - 1972
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260140508
Subject(s) - yield (engineering) , limiting , substrate (aquarium) , biological system , mass transfer , simple (philosophy) , biochemical engineering , oxygen , chemistry , process engineering , computer science , thermodynamics , biology , ecology , chromatography , engineering , physics , mechanical engineering , organic chemistry , philosophy , epistemology
A simple dynamic model is proposed which will allow fermenters to be run at throughputs which fully utilize the mass transfer capabilities of the fermenters while not decreasing the yield from the substrate. The model is compared with one previously proposed, which was originally formulated for double substrate limitation when both substrates were supplied in the feed. Computer solutions of the model are given which show the effects of the parameters used. Experimental results from growing Candida utilis on a high concentration of glucose were found to be similar to those predicted by the model.