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Kinetic model identification in mixed populations using continuous culture data
Author(s) -
Chiu S. Y.,
Erickson L. E.,
Fan L. T.,
Kao I. C.
Publication year - 1972
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260140206
Subject(s) - dilution , aeration , substrate (aquarium) , isothermal process , steady state (chemistry) , serial dilution , chemistry , chemical oxygen demand , washout , bioreactor , chromatography , biological system , pulp and paper industry , environmental science , thermodynamics , environmental engineering , ecology , sewage treatment , biology , medicine , physics , alternative medicine , oceanography , organic chemistry , pathology , engineering , geology
The kinetic behavior of heterogeneous microbial populations of sewage origin was studied in a single‐stage, isothermal, continuous flow, completely mixed aeration tank. A series of experiments were carried out at various dilutions rates using glucose as the limiting substrate. The cell dry weight and substrate concentration in terms of chemical oxygen demand (COD) were continuously monitored. The results indicate that reproducible steady‐state conditions can generally be obtained; however, multiple steady states were observed at dilution rates near washout. At low dilution rates (below about 0.1 hr −1 ) the contribution of microorganism decay became appreciable. Using the multiresponse data of cell dry weight and COD, the parameter values in various existing growth models were estimated. The analyses of variance and residuals revealed that models proposed by Moser, Monod, and Contois, each with a decay term added, were significantly better than the other models which were tested.