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Continuous synchronous culture of Tetrahymena pyroformis
Author(s) -
White Robert W.,
Howell John A.
Publication year - 1971
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260130506
Subject(s) - synchronizing , tetrahymena , remainder , division (mathematics) , chemistry , biology , environmental science , mathematics , microbiology and biotechnology , combinatorics , topology (electrical circuits) , arithmetic
Abstract Tetrahymena was continuously cultivated in a series of stirred tank reactors with recycle. By holding part of the reactor train at a higher temperature than the remainder a synchronizing influence was introduced into the cells' environment. The system resulted in division occurring preferentially in a small contiguous group of the reactors, this effect being observed in both the number of cells found in each reactor and also their size distribution.