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Biogenesis of the L‐N, β‐dimethylleucine residue of etamycin
Author(s) -
Walker John E.,
Perlman D.
Publication year - 1971
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260130304
Subject(s) - biogenesis , methionine , residue (chemistry) , leucine , chemistry , amino acid , biochemistry , antibiotics , stereochemistry , gene
Radioactive labeling experiments have shown that radioactivity from L ‐leucine‐U‐ 14 C is incorporated into the L‐N, β‐dimethylleucine residue of the antibiotic etamycin, and that the N‐methyl and β‐methyl groups of this latter amino acid appear to be derived from L ‐methionine.
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