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Dynamic measurement of the volumetric oxygen transfer coefficient in fermentation systems
Author(s) -
Bandyopadhyay B.,
Humphrey A. E.,
Taguchi H.
Publication year - 1967
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260090408
Subject(s) - aeration , fermentation , oxygen , tracing , chemistry , mass transfer coefficient , analytical chemistry (journal) , chromatography , mass transfer , biochemistry , organic chemistry , computer science , operating system
A rapid and internally consistent technique has been developed to measure the volumetric oxygen transfer coefficient, k L a , in fermentation systems. The method consists of tracing the dissolved O 2 concentration of the fermentation broth during a short interruption of the aeration. The O 2 concentration trace thus obtained can be analyzed to determine the values of k L a . Additional experiments on prolonged O 2 starvation, carried out to find the limitation of the technique, suggest that O 2 uptake rate will vary if a prolonged (2–10 min.) O 2 starvation occurs.