Premium
Studies on automatically aerated biosynthetic processes. II. Occurrence and elimination of CO 2 during penicillin biosynthesis
Author(s) -
Lengyel Z. L.,
Nyiri L.
Publication year - 1966
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260080303
Subject(s) - penicillium chrysogenum , aeration , carbon dioxide , defoamer , oxygen , chemistry , penicillin , biosynthesis , sunflower oil , respiration , hypha , biochemistry , botany , biology , organic chemistry , enzyme , physics , dispersant , antibiotics , optics , dispersion (optics)
Oxygen uptake of Penicillium chrysogenum hyphae growing in automatically aerated deep cultures was the subject of local and periodical change. The change depended on the concentration of carbon dioxide which accumulated in the gas phase of system during the evolution of foam bubbles, and which was suddenly liberated when the foam was destroyed. The actual concentration of sunflower oil added as an antifoaming agent also influenced the oxygen uptake of culture.