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Design and operation of a simple continuous‐culture apparatus
Author(s) -
Saeed Mohammed,
Moss Frank J.
Publication year - 1966
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.260080115
Subject(s) - limiting , simple (philosophy) , continuous flow , process engineering , dilution , computer science , biological system , biochemical engineering , mechanical engineering , biology , engineering , thermodynamics , physics , philosophy , epistemology
A versatile and simple continuous‐culture apparatus is described. With this apparatus, independent control of limiting growth factors and other nutrilites is possible and the conditions of each experiment are reproducible. In view of the synchronized speed of the feeder syringes, flow variation troubles are not encountered. The device allows the performance of growth experiments at different dilution rates simultaneously in a single run which makes the comparison of the results more reliable. The operation of the device has been tested successfully with a study of adenine deaminase induction in yeast.