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Hydrophobic polycationic coatings disinfect poliovirus and rotavirus solutions
Author(s) -
Larson Alyssa M.,
Hsu Bryan B.,
Rautaray Debabrata,
Haldar Jayanta,
Chen Jianzhu,
Klibanov Alexander M.
Publication year - 2011
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.22967
Subject(s) - covalent bond , aqueous solution , coating , poliovirus , polyethylene , chemistry , chemical engineering , polymer science , polymer chemistry , materials science , organic chemistry , virus , virology , biology , engineering
Coating surfaces with N ‐alkylated polyethylenimines (PEIs), namely branched N , N ‐hexyl,methyl‐PEI via covalent attachment to glass or linear N , N ‐dodecyl,methyl‐PEI by physical deposition (“painting”) onto polyethylene, enables the resultant materials to quickly and efficiently disinfect aqueous solutions of (non‐enveloped) poliovirus and rotavirus. Biotechnol. Bioeng. 2011; 108:720–723. © 2010 Wiley Periodicals, Inc.