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Preparation and properties of starch acetate fibers for potential tissue engineering applications
Author(s) -
Reddy Narendra,
Yang Yiqi
Publication year - 2009
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.22331
Subject(s) - starch , tissue engineering , chemical engineering , polysaccharide , modified starch , materials science , chemistry , organic chemistry , biomedical engineering , medicine , engineering
Abstract This article reports the development of fibers from starch acetates that have mechanical properties and water stability better than most polysaccharide‐based biomaterials and protein fibers used in tissue engineering. In this research, starch acetates with three different degrees of substitution (DS) have been used to develop fibers for potential use as tissue engineering scaffolds. Varying the DS of starch acetate will provide fibers with different mechanical properties, hydrophilicity, and degradation behavior. Fibers made from DS 2.3 and 2.8 starch acetates have mechanical properties and water stability required for tissue engineering applications. The starch acetate fibers support the adhesion of fibroblasts demonstrating that the fibers would be suitable for tissue engineering and other medical applications. Biotechnol. Bioeng. 2009;103: 1016–1022. © 2009 Wiley Periodicals, Inc.