Premium
Computational methods in protein structure prediction
Author(s) -
Floudas C.A.
Publication year - 2007
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.21411
Subject(s) - computer science , protein structure prediction , perspective (graphical) , artificial intelligence , protein structure , chemistry , biochemistry
This review presents the advances in protein structure prediction from the computational methods perspective. The approaches are classified into four major categories: comparative modeling, fold recognition, first principles methods that employ database information, and first principles methods without database information. Important advances along with current limitations and challenges are presented. Biotechnol. Bioeng. 2007;97: 207–213. © 2007 Wiley Periodicals, Inc.