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Selective detection and transport of fully matched DNA by DNA‐loaded microtubule and kinesin motor protein
Author(s) -
Taira Shu,
Du YongZhong,
Hiratsuka Yuichi,
Konishi Kaoru,
Kubo Tai,
Uyeda Taro Q.P.,
Yumoto Noboru,
Kodaka Masato
Publication year - 2006
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.21055
Subject(s) - kinesin , dna , motor protein , microtubule , molecular motor , biophysics , biomolecule , chemistry , microbiology and biotechnology , biology , nanotechnology , biochemistry , materials science
DNA‐loaded microtubules (MTs) moving on a kinesin motor protein‐coated substrate can selectively hybridize with a target fully matched DNA over single‐base mismatched DNA and transport it. This technique is capable of collecting target biomolecules toward one point site to design new methodology of DNA analysis. © 2006 Wiley Periodicals, Inc.