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Process monitoring of an industrial fed‐batch fermentation
Author(s) -
Lennox B.,
Montague G.A.,
Hiden H.G.,
Kornfeld G.,
Goulding P.R.
Publication year - 2001
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.1102
Subject(s) - process engineering , monitoring and control , biochemical engineering , fermentation , process (computing) , product (mathematics) , computer science , quality (philosophy) , manufacturing engineering , process control , microbiology and biotechnology , environmental science , engineering , chemistry , control engineering , food science , biology , mathematics , philosophy , geometry , epistemology , operating system
Abstract Market demand places great emphasis in industry on product quality. Consequently, process monitoring and control have become important aspects of systems engineering. In this article we detail the results of a 2‐year study focusing on the development of a condition monitoring system for a fed‐batch fermentation system operated by Biochemie Gmbh in Austria. We also demonstrate the suitability and limitations of current state of the art technologies in this field and suggest novel modifications and configurations to improve their suitability for application to a fed‐batch fermentation system. © 2001 John Wiley & Sons, Inc. Biotechnol Bioeng 74: 125–135, 2001.