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Metabolic database systems for the analysis of genome‐wide function
Author(s) -
Tsoka Sophia,
Ouzounis Christos A.
Publication year - 2003
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.10881
Subject(s) - genome , function (biology) , computational biology , database , variety (cybernetics) , metabolic pathway , biology , computer science , genetics , gene , artificial intelligence
Abstract Genome sequencing projects provide an inventory of molecular components for a wide variety of organisms. Metabolic databases integrate these functional descriptions of individual modules into a higher‐level characterization of cellular metabolism. This article reviews efforts related to the development of metabolic databases and discusses how such systems have aided the delineation of genome properties. We illustrate the design features of metabolic databases and discuss the challenges facing metabolic as well as databases of other functional type. © 2003; Wiley Periodicals, Inc.