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Poly‐3‐hexyl thiophene Langmuir‐Blodgett films for application to glucose biosensor
Author(s) -
Singhal Rahul,
Chaubey Asha,
Kaneto Keiichi,
Takashima W.,
Malhotra B. D.
Publication year - 2003
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/bit.10869
Subject(s) - thiophene , biosensor , chemistry , langmuir–blodgett film , combinatorial chemistry , nanotechnology , materials science , organic chemistry , biochemistry , molecule
Langmuir‐Blodgett films of poly(3‐hexyl thiophene) have been prepared by simultaneous entrapment of glucose oxidase and transferred onto the indium‐tin‐oxide coated glass plates. The films have been characterized by FTIR spectroscopy and detailed response studies have been performed with respect to glucose concentration, temperature, and storage time. These P3HT/SA/GOX electrodes have been utilized for glucose estimation from 100–500 mg/dL by amperometric method. The electrodes have been found to have sensitivity of 0.75 nA/mg/dL detection limit of 50 mg/dL and shelf life of about 75 days at 4°C. © 2004 Wiley Periodicals, Inc.