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Protein dynamics: Rotational diffusion of rigid and fluctuating three dimensional structures
Author(s) -
Perico Angelo,
Guenza Marina,
Mormino Michele,
Fioravanti Roberto
Publication year - 1995
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.360350106
Subject(s) - rotational diffusion , chemistry , rotational dynamics , dynamics (music) , diffusion , classical mechanics , protein dynamics , chemical physics , molecular dynamics , computational chemistry , physics , thermodynamics , molecule , organic chemistry , acoustics
The optimized Rouse‐Zimm approximation to the local dynamics (ORZLD theory) is extended to treat three‐dimensional structures. Rigid model chains of different dimensionality are considered. The local dynamics of random peptides are compared to the rotational correlation times of rigid three‐dimensional protein structures. The treatment of these rigid limits is a necessary step in a more advanced ORZLD theory of the dynamics of proteins including fluctuations relative to the three‐dimensional structure. © 1995 John Wiley & Sons, Inc.