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Interaction of water‐soluble porphyrins with single‐ and double‐stranded polyribonucleotides
Author(s) -
Bustamante Carlos,
Gurrieri Sergio,
Pasternack Robert F.,
Purrello Roberto,
Rizzarelli Enrico
Publication year - 1994
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.360340813
Subject(s) - chemistry , polynucleotide , porphyrin , duplex (building) , water soluble , double stranded , stereochemistry , photochemistry , biochemistry , organic chemistry , dna
CD and uv‐visible absorption studies with several tetracationic water‐soluble porphyrin derivatives show that some of these species can serve as probes to discriminate between A‐ and B‐conformational forms of single‐stranded polynucleotides. It is also observed that these porphyrins can participate in the formation of double helices by forming transient intermediate complexes enroute to duplex formation. © 1994 John Wiley & Sons, Inc.