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Crystal structure of a helical oligopeptide model of polyglycine II and of other polyamides: Acetyl‐(glycyl‐β‐alanyl) 2 ‐ NH propyl
Author(s) -
Tormo José,
Puiggali Jordi,
Vives Joan,
Fita Ignasi,
Lloveras Joaquim,
Bella Jordi,
Aymamí Joan,
Subirana Juan A.
Publication year - 1992
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.360320607
Subject(s) - chemistry , oligopeptide , polyamide , molecule , crystallography , crystal structure , hydrogen bond , chirality (physics) , crystal (programming language) , stereochemistry , polymer chemistry , peptide , organic chemistry , physics , chiral symmetry , biochemistry , quantum mechanics , computer science , nambu–jona lasinio model , programming language , quark
We synthesized and solved the crystalline structure of the oligopeptide acetyl‐ (glycyl‐β‐alanyl) 2 ‐NH propyl. The crystal is formed by layers of helical molecules with the same chirality; however, right‐handed layers alternate with left‐handed ones. Inside every layer, the packing of helices is pseudohexagonal with hydrogen bonds between neighbor molecules. The structure found affords direct support for the model proposed by Crick and Rich for polyglycine II and also provides an interpretation for the structure of a newly found family of polyamides that do not form sheets as observed in most nylon structures.