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Evidential study of correlated events in biochemistry: Physicochemical mechanisms of nucleic acid hydration as revealed by factor analysis
Author(s) -
Starikov E. B.,
Semenov M. A.,
Ya. Maleev V.,
Gasan A. I.
Publication year - 1991
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.360310302
Subject(s) - chemistry , polynucleotide , nucleic acid , biochemistry
Using a factor analysis technique, the experimental physicochemical data on the hydration of mononucleotides, several polynucleotides, their double‐helical complexes and natural DNAs were studied. The information about the factors determining the changes in physicochemical parameters vs the hydration was obtained. This work discusses a possible physical sense of the factors obtained and the expedience of using factor analysis to interpret the molecular‐biophysical experiments.