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On the cooperative binding of large ligands to a one‐dimensional homogeneous lattice: The generalized three‐state lattice model
Author(s) -
Bujalowski Wlodzimierz,
Lohman Timothy M.,
Anderson Charles F.
Publication year - 1989
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.360280912
Subject(s) - cooperativity , lattice (music) , chemistry , homogeneous , omega , cooperative binding , mathematical physics , lattice model (finance) , statistical physics , thermodynamics , physics , quantum mechanics , binding site , organic chemistry , polymer , biochemistry , acoustics
We present the general secular equation for three‐state lattice models for the cooperative binding of large ligands to a one‐dimensional lattice. In addition, a closed‐form expression for the isotherm is also obtained, that can be used with all values of the cooperativity parameter ω(0 < ω < ∞) thus eliminating the need for multiple equations.